Visible Changes by Boosting Collagen – A Science-Backed Approach, Microneedling for Stretch Marks.
Stretch marks are a common concern, but microneedling treatments like PRP, exosomes, and RF can help improve their appearance over time. This blog explores how each treatment works, their effectiveness based on clinical studies and patient reviews, and the expected costs. Learn how gradual healing makes early treatment a smart choice—even before pregnancy. Find out which microneedling option is best for you!

Stretch marks, or striae distensae, are a common concern for many people. Whether caused by pregnancy, weight fluctuations, or growth spurts, these marks can be challenging to treat. Fortunately, microneedling—a procedure that stimulates collagen production—has proven to be an effective way to reduce the appearance of stretch marks.
There are several variations of microneedling treatments available, including microneedling with PRP (Platelet-Rich Plasma), exosomes, stem cells, and RF (radiofrequency) microneedling. But which one is the most effective? And what are the costs? Let’s break it down in a way that’s easy to understand.
How Does Microneedling Work for Stretch Marks?
Microneedling involves using fine needles to create tiny injuries in the skin, stimulating collagen and elastin production. This helps repair damaged skin and improve the appearance of stretch marks over time. Healing is gradual, meaning that improvements become more noticeable over several weeks to months after treatment. This natural process allows for long-lasting skin remodeling and regeneration.
Different Types of Microneedling Treatments
- Microneedling with PRP – Uses your own blood’s growth factors to boost healing.
- Microneedling with Exosomes – Uses lab-derived cellular messengers to enhance skin regeneration.
- RF Microneedling – Adds radiofrequency energy to tighten and rejuvenate skin.
- Microneedling with Stem Cells – Uses stem cell-derived products to promote deep skin renewal.
Microneedling with PRP (Platelet-Rich Plasma)
Effectiveness Based on Clinical Studies
- A study of 30 patients found that microneedling with PRP was significantly more effective than microneedling alone, with 86.6% of patients reporting high satisfaction. (Kaur et al., 2024)
- Another study of 40 patients showed greater collagen and elastin production in the PRP-treated group. (Abdel-Motaleb et al., 2022)
- However, PRP’s effects are generally mild to moderate, and some studies show that fractional lasers may be more effective for severe stretch marks. (Tayal et al., 2024)
Effectiveness Based on Patient Reviews
- Pros: Many patients report smoother skin and lighter stretch marks after 3-6 sessions.
- Cons: Some patients say the changes are minimal and may not justify the cost.
- PRP microneedling has an 82% "Worth It" rating on RealSelf.
Cost Estimate:
$200 - $600 per session (varies by clinic and location)
Micro-needling with Exosomes
Effectiveness Based on Clinical Studies
- A 2023 trial of exosome microneedling for old (white) stretch marks found noticeable improvement, though the effect was comparable to PRP. (Faghihi et al., 2023)
- Exosomes contain over 100 growth factors, compared to PRP’s 10-15, making them potentially more powerful in stimulating collagen. (Huang et al., 2024)
- However, long-term studies are still limited, and more research is needed.
Effectiveness Based on Patient Reviews
- Pros: Patients report faster healing, improved texture, and better skin tone compared to microneedling alone.
- Cons: Since exosome therapy is newer, fewer reviews exist. Some patients find results similar to PRP.
- Exosome treatments tend to have high patient satisfaction but lack extensive studies.
Cost Estimate
$500 - $1,200 per session (higher due to lab-processing costs)
RF (Radiofrequency) Microneedling
Effectiveness Based on Clinical Studies
- RF microneedling outperformed traditional microneedling in stretch mark reduction in a meta-analysis of 11 studies. (Huang et al., 2024)
- One study found a 21.6% reduction in stretch mark depth after RF microneedling. (Tayal et al., 2024)
- RF microneedling is often as effective as laser treatments but with fewer side effects. (Lim et al., 2023)
Effectiveness Based on Patient Reviews
- Pros: Patients report stronger skin tightening and deeper improvement in texture compared to PRP or exosomes.
- Cons: It can be painful (requires numbing cream) and may cause small scabs for a few days.
- RF microneedling has a 70-75% "Worth It" rating on RealSelf.
Cost Estimate
$500 - $1,500 per session (varies based on device and provider)
Should You Wait Until After Pregnancy?
Many women worry that their stretch marks will return or worsen after pregnancy and believe they should wait before treating them. However, since microneedling leads to gradual skin healing, waiting until after pregnancy is not necessary. Starting treatment earlier can help build collagen over time, strengthening the skin and making future stretch marks less noticeable. If new stretch marks develop later, additional maintenance treatments can further improve skin quality.
Final Recommendations
- If you have new stretch marks (red/pink), microneedling alone or with PRP can be a great option.
- For older stretch marks (white/silver), RF microneedling or exosomes may give better results.
- If you want the most powerful option, RF microneedling has the best clinical data.
- Consider your budget—exosomes and stem cell treatments can be expensive.
For the best results, we recommend a consultation to determine the right plan for your skin. Book an appointment at AuraDent Aesthetic Clinic today to explore your options!
References
- Kaur T et al. (2024). Microneedling vs. Microneedling+PRP for stretch marks. J. Cutan. Aesthet. Surg.
- Abdel-Motaleb AA et al. (2022). Microneedling with PRP vs microneedling alone for striae. J Dermatolog Treat.
- Huang L et al. (2024). Microneedling Therapy for Striae: Meta-Analysis. Aesthetic Plast Surg.
- Tayal A et al. (2024). Fractional CO₂ Laser vs. Microneedling with PRP. Natl J Med Res.
- Faghihi G et al. (2023). Exosome Therapy for Striae Alba. J. Dermatolog. Treat.
Want to learn more? Contact us at AuraDent Aesthetic Clinic!